Publications
1.
Fang, Lichen; Yan, Yishu; Agarwal, Ojaswi; Seppala, Jonathan E.; Hemker, Kevin J.; Kang, Sung Hoon
Processing-structure-property relationships of bisphenol-A-polycarbonate samples prepared by fused filament fabrication Journal Article
In: Additive Manufacturing, vol. 35, 2020.
@article{Fang2020,
title = {Processing-structure-property relationships of bisphenol-A-polycarbonate samples prepared by fused filament fabrication},
author = {Lichen Fang and Yishu Yan and Ojaswi Agarwal and Jonathan E. Seppala and Kevin J. Hemker and Sung Hoon Kang},
url = {https://www.sciencedirect.com/science/article/pii/S2214860420306576},
doi = {https://doi.org/10.1016/j.addma.2020.101285},
year = {2020},
date = {2020-05-11},
journal = {Additive Manufacturing},
volume = {35},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
2.
Jung, Wei-Hung; Elawad, Khalid; Kang, Sung Hoon; Chen, Yun
Cell–Cell Adhesion and Myosin Activity Regulate Cortical Actin Assembly in Mammary Gland Epithelium on Concaved Surface Journal Article
In: Cells, vol. 8, no. 8, pp. 813, 2019.
@article{Jung2019,
title = {Cell–Cell Adhesion and Myosin Activity Regulate Cortical Actin Assembly in Mammary Gland Epithelium on Concaved Surface},
author = {Wei-Hung Jung and Khalid Elawad and Sung Hoon Kang and Yun Chen},
url = {https://www.mdpi.com/2073-4409/8/8/813},
doi = {10.3390/cells8080813},
year = {2019},
date = {2019-08-02},
journal = {Cells},
volume = {8},
number = {8},
pages = {813},
abstract = {It has been demonstrated that geometry can affect cell behaviors. Though curvature-sensitive proteins at the nanoscale are studied, it is unclear how cells sense curvature at the cellular and multicellular levels. To characterize and determine the mechanisms of curvature-dependent cell behaviors, we grow cells on open channels of the 60-µm radius. We found that cortical F-actin is 1.2-fold more enriched in epithelial cells grown on the curved surface compared to the flat control. We observed that myosin activity is required to promote cortical F-actin formation. Furthermore, cell-cell contact was shown to be indispensable for curvature-dependent cortical actin assembly. Our results indicate that the actomyosin network coupled with adherens junctions is involved in curvature-sensing at the multi-cellular level.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
It has been demonstrated that geometry can affect cell behaviors. Though curvature-sensitive proteins at the nanoscale are studied, it is unclear how cells sense curvature at the cellular and multicellular levels. To characterize and determine the mechanisms of curvature-dependent cell behaviors, we grow cells on open channels of the 60-µm radius. We found that cortical F-actin is 1.2-fold more enriched in epithelial cells grown on the curved surface compared to the flat control. We observed that myosin activity is required to promote cortical F-actin formation. Furthermore, cell-cell contact was shown to be indispensable for curvature-dependent cortical actin assembly. Our results indicate that the actomyosin network coupled with adherens junctions is involved in curvature-sensing at the multi-cellular level.
3.
Grinthal, Alison; Kang, Sung Hoon; Epstein, Alexander K.; Aizenberg, Michael; Khan, Mughees; Aizenberg, Joanna
Steering Nanofibers: An Integrative Approach to Bio-Inspired Fiber Fabrication and Assembly Journal Article
In: Nano Today, vol. 7, pp. 35-52, 2012, (Invited Review).
@article{Grinthal2012,
title = {Steering Nanofibers: An Integrative Approach to Bio-Inspired Fiber Fabrication and Assembly},
author = {Alison Grinthal and Sung Hoon Kang and Alexander K. Epstein and Michael Aizenberg and Mughees Khan and Joanna Aizenberg},
url = {http://www.sciencedirect.com/science/article/pii/S1748013211001411},
year = {2012},
date = {2012-02-01},
journal = {Nano Today},
volume = {7},
pages = {35-52},
abstract = {As seen throughout the natural world, nanoscale fibers exhibit a unique combination of mechanical and surface properties that enable them to wind and bend around each other into an immense diversity of complex forms. In this review, we discuss how this versatility can be harnessed to transform a simple array of anchored nanofibers into a variety of complex, hierarchically organized dynamic functional surfaces. We describe a set of recently developed benchtop techniques that provide a straightforward way to generate libraries of fibrous surfaces with a wide range of finely tuned, nearly arbitrary geometric, mechanical, material, and surface characteristics starting from a single master array. These simple systematic controls can be used to program the fibers to bundle together, twist around each other into chiral swirls, and assemble into patterned arrays of complex hierarchical architectures. The delicate balance between fiber elasticity and surface adhesion plays a critical role in determining the shape, chirality, and higher order of the assembled structures, as does the dynamic evolution of the geometric, mechanical, and surface parameters throughout the assembly process. Hierarchical assembly can also be programmed to run backwards, enabling a wide range of reversible, responsive behaviors to be encoded through rationally chosen surface chemistry. These strategies provide a foundation for designing a vast assortment of functional surfaces with anti-fouling, adhesive, optical, water and ice repellent, memory storage, microfluidic, capture and release, and many more capabilities with the structural and dynamic sophistication of their biological counterparts.},
note = {Invited Review},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
As seen throughout the natural world, nanoscale fibers exhibit a unique combination of mechanical and surface properties that enable them to wind and bend around each other into an immense diversity of complex forms. In this review, we discuss how this versatility can be harnessed to transform a simple array of anchored nanofibers into a variety of complex, hierarchically organized dynamic functional surfaces. We describe a set of recently developed benchtop techniques that provide a straightforward way to generate libraries of fibrous surfaces with a wide range of finely tuned, nearly arbitrary geometric, mechanical, material, and surface characteristics starting from a single master array. These simple systematic controls can be used to program the fibers to bundle together, twist around each other into chiral swirls, and assemble into patterned arrays of complex hierarchical architectures. The delicate balance between fiber elasticity and surface adhesion plays a critical role in determining the shape, chirality, and higher order of the assembled structures, as does the dynamic evolution of the geometric, mechanical, and surface parameters throughout the assembly process. Hierarchical assembly can also be programmed to run backwards, enabling a wide range of reversible, responsive behaviors to be encoded through rationally chosen surface chemistry. These strategies provide a foundation for designing a vast assortment of functional surfaces with anti-fouling, adhesive, optical, water and ice repellent, memory storage, microfluidic, capture and release, and many more capabilities with the structural and dynamic sophistication of their biological counterparts.
Note: Send e-mail to Prof. Kang at [email protected] if you need a pdf file of the papers below.
2020
Fang, Lichen; Yan, Yishu; Agarwal, Ojaswi; Seppala, Jonathan E.; Hemker, Kevin J.; Kang, Sung Hoon
Processing-structure-property relationships of bisphenol-A-polycarbonate samples prepared by fused filament fabrication Journal Article
In: Additive Manufacturing, vol. 35, 2020.
Links | BibTeX | Tags: 3D printing, Geometry, mechancal properties, modulus, toughness
@article{Fang2020,
title = {Processing-structure-property relationships of bisphenol-A-polycarbonate samples prepared by fused filament fabrication},
author = {Lichen Fang and Yishu Yan and Ojaswi Agarwal and Jonathan E. Seppala and Kevin J. Hemker and Sung Hoon Kang},
url = {https://www.sciencedirect.com/science/article/pii/S2214860420306576},
doi = {https://doi.org/10.1016/j.addma.2020.101285},
year = {2020},
date = {2020-05-11},
journal = {Additive Manufacturing},
volume = {35},
keywords = {3D printing, Geometry, mechancal properties, modulus, toughness},
pubstate = {published},
tppubtype = {article}
}
2019
Jung, Wei-Hung; Elawad, Khalid; Kang, Sung Hoon; Chen, Yun
Cell–Cell Adhesion and Myosin Activity Regulate Cortical Actin Assembly in Mammary Gland Epithelium on Concaved Surface Journal Article
In: Cells, vol. 8, no. 8, pp. 813, 2019.
Abstract | Links | BibTeX | Tags: 3D printing, cell behaviors, curvature sensing, Geometry, multi-cellular
@article{Jung2019,
title = {Cell–Cell Adhesion and Myosin Activity Regulate Cortical Actin Assembly in Mammary Gland Epithelium on Concaved Surface},
author = {Wei-Hung Jung and Khalid Elawad and Sung Hoon Kang and Yun Chen},
url = {https://www.mdpi.com/2073-4409/8/8/813},
doi = {10.3390/cells8080813},
year = {2019},
date = {2019-08-02},
journal = {Cells},
volume = {8},
number = {8},
pages = {813},
abstract = {It has been demonstrated that geometry can affect cell behaviors. Though curvature-sensitive proteins at the nanoscale are studied, it is unclear how cells sense curvature at the cellular and multicellular levels. To characterize and determine the mechanisms of curvature-dependent cell behaviors, we grow cells on open channels of the 60-µm radius. We found that cortical F-actin is 1.2-fold more enriched in epithelial cells grown on the curved surface compared to the flat control. We observed that myosin activity is required to promote cortical F-actin formation. Furthermore, cell-cell contact was shown to be indispensable for curvature-dependent cortical actin assembly. Our results indicate that the actomyosin network coupled with adherens junctions is involved in curvature-sensing at the multi-cellular level.},
keywords = {3D printing, cell behaviors, curvature sensing, Geometry, multi-cellular},
pubstate = {published},
tppubtype = {article}
}
It has been demonstrated that geometry can affect cell behaviors. Though curvature-sensitive proteins at the nanoscale are studied, it is unclear how cells sense curvature at the cellular and multicellular levels. To characterize and determine the mechanisms of curvature-dependent cell behaviors, we grow cells on open channels of the 60-µm radius. We found that cortical F-actin is 1.2-fold more enriched in epithelial cells grown on the curved surface compared to the flat control. We observed that myosin activity is required to promote cortical F-actin formation. Furthermore, cell-cell contact was shown to be indispensable for curvature-dependent cortical actin assembly. Our results indicate that the actomyosin network coupled with adherens junctions is involved in curvature-sensing at the multi-cellular level.
2012
Grinthal, Alison; Kang, Sung Hoon; Epstein, Alexander K.; Aizenberg, Michael; Khan, Mughees; Aizenberg, Joanna
Steering Nanofibers: An Integrative Approach to Bio-Inspired Fiber Fabrication and Assembly Journal Article
In: Nano Today, vol. 7, pp. 35-52, 2012, (Invited Review).
Abstract | Links | BibTeX | Tags: Assembly, Bio-Inspired, bio-inspired science and engineering, Chemistry, Fabrication, Geometry, Hierarchical, Mechanics, Nanofiber, Symmetry
@article{Grinthal2012,
title = {Steering Nanofibers: An Integrative Approach to Bio-Inspired Fiber Fabrication and Assembly},
author = {Alison Grinthal and Sung Hoon Kang and Alexander K. Epstein and Michael Aizenberg and Mughees Khan and Joanna Aizenberg},
url = {http://www.sciencedirect.com/science/article/pii/S1748013211001411},
year = {2012},
date = {2012-02-01},
journal = {Nano Today},
volume = {7},
pages = {35-52},
abstract = {As seen throughout the natural world, nanoscale fibers exhibit a unique combination of mechanical and surface properties that enable them to wind and bend around each other into an immense diversity of complex forms. In this review, we discuss how this versatility can be harnessed to transform a simple array of anchored nanofibers into a variety of complex, hierarchically organized dynamic functional surfaces. We describe a set of recently developed benchtop techniques that provide a straightforward way to generate libraries of fibrous surfaces with a wide range of finely tuned, nearly arbitrary geometric, mechanical, material, and surface characteristics starting from a single master array. These simple systematic controls can be used to program the fibers to bundle together, twist around each other into chiral swirls, and assemble into patterned arrays of complex hierarchical architectures. The delicate balance between fiber elasticity and surface adhesion plays a critical role in determining the shape, chirality, and higher order of the assembled structures, as does the dynamic evolution of the geometric, mechanical, and surface parameters throughout the assembly process. Hierarchical assembly can also be programmed to run backwards, enabling a wide range of reversible, responsive behaviors to be encoded through rationally chosen surface chemistry. These strategies provide a foundation for designing a vast assortment of functional surfaces with anti-fouling, adhesive, optical, water and ice repellent, memory storage, microfluidic, capture and release, and many more capabilities with the structural and dynamic sophistication of their biological counterparts.},
note = {Invited Review},
keywords = {Assembly, Bio-Inspired, bio-inspired science and engineering, Chemistry, Fabrication, Geometry, Hierarchical, Mechanics, Nanofiber, Symmetry},
pubstate = {published},
tppubtype = {article}
}
As seen throughout the natural world, nanoscale fibers exhibit a unique combination of mechanical and surface properties that enable them to wind and bend around each other into an immense diversity of complex forms. In this review, we discuss how this versatility can be harnessed to transform a simple array of anchored nanofibers into a variety of complex, hierarchically organized dynamic functional surfaces. We describe a set of recently developed benchtop techniques that provide a straightforward way to generate libraries of fibrous surfaces with a wide range of finely tuned, nearly arbitrary geometric, mechanical, material, and surface characteristics starting from a single master array. These simple systematic controls can be used to program the fibers to bundle together, twist around each other into chiral swirls, and assemble into patterned arrays of complex hierarchical architectures. The delicate balance between fiber elasticity and surface adhesion plays a critical role in determining the shape, chirality, and higher order of the assembled structures, as does the dynamic evolution of the geometric, mechanical, and surface parameters throughout the assembly process. Hierarchical assembly can also be programmed to run backwards, enabling a wide range of reversible, responsive behaviors to be encoded through rationally chosen surface chemistry. These strategies provide a foundation for designing a vast assortment of functional surfaces with anti-fouling, adhesive, optical, water and ice repellent, memory storage, microfluidic, capture and release, and many more capabilities with the structural and dynamic sophistication of their biological counterparts.